Antibiotics for treating bacteria and for treating fungi are completely different. The most common antibiotic used in gynecology for treating bacteria is metronidazole, which is ineffective against fungi, and Lactobacillus, which exists as a normal flora and is also naturally resistant to metronidazole, so for vaginitis or vaginosis caused by anaerobic bacteria, metronidazole is the drug of choice. All other types of antibiotics generally require careful evaluation and a clear purpose for use if they are needed for vaginitis. Commonly used drugs for vaginal fungal infections are Daflucan and Spironolactone, but of course other antifungal drugs are also available, which are usually ineffective against common bacteria.