Parkinson’s disease is a chronic progressive disease, and obtaining long-term stable efficacy is the goal of treatment. If the treatment is inadequate due to excessive concern about side effects, the patient’s symptoms will be heavier and affect daily life and work; if a large number of drugs are used to pursue short-term efficacy, although the short-term symptom relief is more adequate, the long-term side effects will plague the patient’s future life. Therefore, a balanced selection of medications, taking into account both immediate and long-term efficacy, and balancing efficacy and risk is a reasonable choice. Specific considerations include the following: Avoidance of falls should be the minimum goal of treatment. If unstable standing is an indication that treatment is inadequate, an increase in medication or dose needs to be considered. Treatment to a more “normal” state suggests that treatment may be excessive. There is a higher risk of drug complications. If motor fluctuations and switching periods occur, aim for 2/3 of the time to be on without sleep, denying the need to increase medication and dose. As the disease progresses, treatment must be adjusted accordingly. It is important to be prepared for long-term treatment and to have different treatments at different stages of the disease. Treatment for Parkinson’s disease varies widely, and the medications or treatments that are appropriate for each person may vary, and subtle differences can have a big impact. Each person with Parkinson’s disease should develop a treatment plan after a systematic scientific evaluation, which includes Evaluation of the type and degree of symptoms Evaluation of the response to medications Systematic examination of the nervous system, including molecular imaging of the brain, nuclear magnetic examination, etc.