Clinically, isobarbital generic name verapamil is mainly used for all types of angina, including stable or unstable angina, and variant angina; atrial premature beats, prevention of paroxysmal supraventricular tachycardia; hypertrophic cardiomyopathy and hypertension. Therefore, it can be used for atrial premature beats. Atrial premature beats are divided into physiological and pathological, physiological atrial premature beats can be seen in normal people, usually occurs when exertion, excitement, can be relieved by themselves, do not need treatment. Pathologic premature beats can be treated with isobaric pacing. 1. Isobutynin is verapamil, a non-dihydropyridine calcium antagonist. It can selectively block calcium channels on the membrane of myocardial and vascular smooth muscle cells and inhibit the function of the sinus node and atrioventricular node, so as to play a role in weakening myocardial contraction, dilating blood vessels, lowering blood pressure and slowing down the heart rate. 2. The adverse effects of this product are mostly dose-related. When the dose is used inappropriately, bradycardia, atrioventricular block, cardiac arrest, heart failure, hypotension and other manifestations may occur. It may also cause dizziness or vertigo, allergic reactions and increased plasma prolactin concentration or breast-feeding. 3. It should be noted that isobaric is contraindicated in patients with severe left ventricular insufficiency, hypotension or cardiogenic shock, morbid sinus node syndrome, second or third degree atrioventricular block, atrial flutter or atrial fibrillation combined with atrioventricular bypass channels and in patients allergic to verapamil. When using the drug must be under the guidance of a specialist, strictly grasp the indications and choose the appropriate dose.