Nodular disease is a multisystemic disease of unknown etiology, characterized by granulomas, which can affect multiple organs and the systemic lymphatic system, of which intrathoracic nodular disease accounts for 80-90%, with a male to female ratio of approximately 1:1.72 abroad, with more women than men. There are slight differences in domestic reports. The cause of the disease is still unclear and may be related to infection, metabolic reaction, chemical stimulation, drugs, autoimmunity, etc. Clinical manifestations: slow onset, no symptoms and signs in the early stage, with the progression of the disease may appear: weakness, low fever, night sweats, chest tightness, cough, spitting white sputum, coughing blood, shortness of breath, poor appetite, weight loss, etc. 1. Diagnostic points: 1. X-ray: chest film or CT can be seen in bilateral hilar lymph nodes enlargement, into potato-like masses, and scattered lung nodules, and reticular shadows, late hilar lymph nodes can fade, leaving intra-pulmonary lesions, some patients appear pulmonary fibrosis. It is often divided into four stages according to the X-ray presentation Stage I: enlarged hilar lymph nodes with no lung abnormalities; Stage II: diffuse small nodular lesions in the lung with hilar lymph node enlargement; Stage III: diffuse lesions in the lung with no hilar lymph nodes; Stage IV: pulmonary fibrosis. 2, laboratory tests: increased angiotensin-converting enzyme (SACE) in blood; high serum metalloendopeptidase assay, collagenase activity assay, – contribute to the diagnosis, positive nodular disease skin test (kveim); negative tuberculin test; blood calcium may be increased. Increased neutrophilic leukocytes and lymphocytes in bronchoscopic lavage fluid. Pulmonary function tests About 20% of people have impaired lung function , appearing hyperventilation and diffusion function. Pathological examination: superficial lymph node biopsy, bronchial mucosal biopsy, transbronchoscopic lung biopsy can confirm the diagnosis by seeing the typical pathological changes of non-stem necrotizing granuloma. Western medical treatment: Currently, the disease responds well to hormonal therapy, but the course of treatment is long and the recurrence rate is high. Immunosuppressive therapy such as azathioprine, cyclophosphamide, etc. has certain efficacy, but there are more side effects, and there are also people who apply rhodopsin, cyclosporine A as corticosteroid treatment is ineffective or alternative treatment, and in recent years there are people who use cytokine therapy, the efficacy and side effects of these drugs are yet to be further evaluated. Chinese medicine treatment: At present, there is no special name for this disease in Chinese medicine literature, it should belong to the category of lung paralysis, lung impotence, phlegm drink, gall tumor, etc.. It is believed that the pathogenesis of the disease may be related to the weakness of the organs of the body and the damage to the vital energy caused by external attack, such as strain, diet, emotion, and external sensation. The Su Wen. Xuanming five qi chapter emphasizes that “five labor injuries, long vision injury blood, long lying injury qi, long sitting injury flesh, long standing injury bone, long walking injury tendons” pointed out the impact of internal injury factors of deficiency labor on the organism. Deficiency of blood and qi leads to loss of fluids, and the organs lose moistening and dryness, which affects the lungs. In Jing Yue Quan Shu, it is said that paralysis is also closed by blood and qi, and blood stops as silt, and dampness condenses as phlegm, blocking the blood vessels and meridians so that evil stays in the chest and lungs. Su Wen. It is said in the general commentary on deficiency and reality that the seizure of essence is deficient, and the deficiency of qi and blood and lung heat and leaf anxiety is the cause of atrophy. Zhongzangjing. Five paralysis” said: “paralysis, wind, cold, stormy dampness in the human viscera as well. We believe that the disease should be a deficiency of the root and the symptoms. The disease is caused by a deficiency of qi and blood in the organism, and the dysfunction of the internal organs, which leads to the blockage of qi flow. Based on years of experience, we believe that nodular disease should be treated according to the following classification and typology, which has good clinical effect after years of clinical observation. The treatment is based on the following syndrome typology. The treatment is to tonify the lung and benefit the qi, soften the hardness and disperse the nodules. 2, deficiency of both lung and spleen, phlegm-heat injury to the lung: gastric fullness, abdominal distension, poor appetite, fatigue, shortness of breath, cough, red eyes, pale tongue with yellow coating or greasy treatment: strengthen the spleen and benefit the qi, soften the hardness and disperse the nodules. Treatment: Benefit qi, nourish yin, invigorate blood and remove blood stasis. 4. Spleen and kidney deficiency: weakness, cough with shortness of breath, white and thick phlegm, night sweating, five heartburn, unheated extremities, abdominal distension, loose stools, palpitations, swelling of the lower extremities. Thin white teeth marks on the tongue, sunken pulse. Treatment: Tonify the kidneys and strengthen the spleen, dispel blood stasis and disperse nodules. Combination of Chinese and Western medicine treatment In recent years, we have adopted Chinese medicine evidence-based treatment, combined Chinese and Western medicine treatment, and Chinese medicine soup combined with microhormone inhalation therapy. Many clinical patients have been cured. Applying the above dialectical treatment. In particular, we have achieved good clinical results in patients with more nodular lesions in the lungs, more severe coughing symptoms, poor hormone treatment and recurrent attacks.