Adrenal outgrowth nodules are often asymptomatic. They are usually found incidentally during a physical examination, or when checking for kidney disease. These nodules are most likely to be primary adrenal hyperplasia, adrenal tuberculosis or adrenal cysts. However, due to the adrenal medulla, sympathetic ganglion and other parts of the adrenal gland may appear some tumor conditions. Therefore, the discovery of adrenal nodules should be detailed adrenal imaging and testing. Adrenal ct scan or MRI scan is usually needed. If necessary, radionuclide labeling should be applied, and blood and urine tests for catecholamines and their metabolites should be performed. To help determine the presence or absence of neuroendocrine effects of this adrenal nodule. If the above tests indicate that the adrenal nodule may be tumorigenic, the adrenal nodule may have a neuroendocrine effect. And there may be some corresponding symptoms after the appearance of adrenal nodules, such as high blood pressure, fever, wasting, increased blood sugar, hypercalcemia and other conditions. Then we need to consider whether it is adrenal pheochromocytoma or other tumors. That can be treated by surgical removal. Most adrenal tumors are benign. A few malignant adrenal pheochromocytomas are more difficult to treat. In conclusion, some of the adrenal nodules have no symptoms and do not require treatment, if they do, they need to be seen promptly and treated surgically if necessary.