There are many diseases that can cause the clinical manifestations of weakness and shortness of breath, such as tuberculosis in young adults, lung tumors in the elderly, hyperthyroid heart disease due to hyperthyroidism, and so on. When a patient develops these symptoms, he or she should actively seek medical attention, improve relevant tests, clarify the diagnosis, and give appropriate treatment according to the diagnosis. If the patient has weakness and shortness of breath due to pulmonary tuberculosis, he or she should be treated with anti-tuberculosis drugs, including isoniazid, rifampin, pyrazinamide, streptomycin, etc. If the patient suffers from weakness and shortness of breath due to lung tumor, surgery, radiotherapy, chemotherapy or target cell drugs should be given according to the condition. If the patient suffers from cardiac insufficiency due to hyperthyroid heart disease or coronary heart disease, cardiac strengthening, diuretic and vasodilator therapy should be given according to the condition.