Under normal conditions, pancreatic juice contains inactive pancreatic zymogen in its glandular tissue. The pancreatic juice flows continuously along the pancreatic duct through the sphincter of Oddi of the common bile duct into the duodenum, and due to the presence of bile in the duodenum and the secretion of an intestinal kinase by the mucosa of the duodenal wall, the pancreatic zymogen starts to turn into a very active digestive enzyme under the action of both. If the outflow tract is obstructed and the excretion is not smooth, pancreatitis can be caused. When the sphincter of Oddi spasms or the pressure in the bile duct rises, such as stones or tumor obstruction, the bile will flow back into the pancreatic duct and enter the pancreatic tissue, at this time, the lecithin contained in the bile is broken down by the lecithin enzyme contained in the pancreatic juice into lysolecithin, which can have a toxic effect on the pancreas. In the case of biliary tract infection, bacteria can release kinases that activate pancreatic enzymes, which can also become active substances that can damage and lyse pancreatic tissues. These substances convert the pancreatic zymogen contained in the pancreatic fluid into pancreatic protease, which has strong digestive activity and penetrates into the pancreatic tissue to cause self-digestion, which can also cause pancreatitis. Acute pancreatitis is an acute inflammation caused by pancreatic enzymes digesting the pancreas and its surrounding tissues, mainly manifesting as edema, hemorrhage and necrosis of the pancreas. (1) Biliary system disease bile duct inflammation, stones, parasites, edema, spasm and other lesions that cause obstruction in the jugular abdomen, bile flowing back into the pancreatic duct through the common channel, activating pancreatic zymogen, thus causing pancreatitis. (2) Alcoholism and overeating alcoholism and overeating make the pancreatic juice secretion strong, and poor drainage of the pancreatic duct, resulting in increased pressure of the pancreatic juice in the pancreaticobiliary system, resulting in high concentration of protease excretion obstruction, and finally leading to the rupture of the pancreatic vesicles and the onset of disease. (3) Surgery and injury, such as stomach and biliary tract abdominal surgery squeeze the pancreas, or cause excessive pressure in the pancreaticobiliary duct. (4) Many infectious diseases can be complicated by acute pancreatitis, and the symptoms are not obvious. If roundworms enter the bile duct or pancreatic duct, they can bring in bacteria that can activate pancreatic enzymes and cause pancreatic inflammation. (5) hyperlipidemia and hypercalcemia hyperlipidemia, fat embolism of the pancreatic vessels causing local ischemia, capillary dilation, damage to the vessel wall, resulting in difficulty in the excretion of pancreatic juice; stones can block the pancreatic ducts, causing pancreatitis. Chronic pancreatitis is a disease of chronic progressive destruction of the pancreas caused by repeated episodes of acute pancreatitis.