Tumor recurrence is very common in clinical practice. Many tumor patients are cured or clinically cured after various effective treatments, but after a period of time, the cured tumor recurs again, which brings pain and threat to the recovering or recovered patients again. What can be done to prevent or reduce the recurrence of tumor? First of all, the treatment of tumor should be as thorough as possible. This is very easy to achieve for early stage tumors, and the planned comprehensive treatment with radical surgery and reasonable radiotherapy and chemotherapy can prevent recurrence completely. Although the technology of tumor treatment is getting more and more advanced, it is still very difficult to achieve absolute completeness through one-time or surprise treatment, especially for middle and advanced stage tumors, that is, it is very difficult to avoid some tumor cells remaining in the body. The purpose of anti-relapse therapy is to destroy the remaining tumor cells after treatment or to inhibit the further development of undetected tumors. Some scholars advocate that after the tumor has been treated with surgery, radiotherapy or high-dose chemotherapy and the clinical symptoms have disappeared, anti-recurrence treatment should be maintained for more than five years. Generally, it is four courses of chemotherapy for 30-40 days each year based on the original cure. As for the specific anti-relapse treatment, it should be carried out under the guidance of doctors depending on the actual situation of patients and disease types. Secondly, to eliminate or avoid the factors that contribute to the recurrence of tumor and actively treat the chronic diseases related to tumor. The physical and chemical factors and biological carcinogenic factors that cause tumor as mentioned above can still induce tumor recurrence, so they should be eliminated and avoided as much as possible. Special attention should also be paid to some internal factors. For example, women of childbearing age who have suffered from breast cancer should use absolute contraception to avoid the recurrence of breast cancer. All tumor patients should pay attention to keep their mood happy and relaxed, avoiding long-term and excessive mental tension and bad stimulation. The presence of certain chronic diseases may lower the immune function of the body and affect the local or general functional status of the patient, and may induce the recurrence of tumor, so active treatment should be given. In addition, to strengthen physical exercise and improve immune function and disease resistance of the body is also an effective way to prevent tumor recurrence. It is also an important part to prevent tumor recurrence effectively. In the process of recovery after tumor cure, some exercises suitable for patients should be carried out according to the actual situation, such as qigong, jogging, taijiquan and so on. The function is to enhance the recovery of the patient’s body functions, mobilize the positive factors of the whole body, enhance the resistance to disease and reduce the chance of tumor recurrence. Finally, we should pay attention to regular or frequent re-examination. This is the most important remedial measure after the failure of recurrence prevention, and it is also a point that all tumor patients should pay attention to after cure. The review includes patient’s self-examination and hospital’s regular examination. The main purpose of self-examination is to observe whether there are new swellings, ruptures, nodules and other manifestations in and around the original lesions, and whether there are new painful sensations. In addition, patients should also pay attention to the changes of their body, whether there are gradually increasing weakness, loss of appetite, anemia, weight loss, etc. Once these conditions appear, they should go to hospital for examination in time. Although recurrent tumors are more difficult to treat than the primary tumors, they can be cured with early detection, early diagnosis and early treatment.