Nationally recognized and currently clinically used medications for the treatment of premature ejaculation are consistent, including 5-hydroxytryptamine reuptake inhibitors, tricyclic antidepressants, and topical local anesthetics. Premature ejaculation is one of the types of male sexual dysfunction. Its etiology may be the result of early unpleasant sexual experiences, stress, abnormal hormone levels, and genetic susceptibility. Usually, most patients with premature ejaculation can take oral 5-hydroxytryptamine reuptake inhibitors, such as dapoxetine hydrochloride, paroxetine, and sertraline, under the supervision of a doctor. Or oral tricyclic antidepressants such as chlorpromazine, or topical anesthetics such as lidocaine. If the patient has premature ejaculation, should go to the regular hospital, under the guidance of the doctor to take relevant therapeutic measures, so as not to delay the condition. In daily life, need to ensure a positive and optimistic mindset, appropriate exercise, so as to enhance physical fitness.