Headache caused by coughing is considered to be caused by the excitation of the vagus nerve due to violent coughing, which in turn causes the blood vessels in the head to dilate, resulting in headache. In addition, the cause of the cough, such as a cold, also has symptoms of headache, so treatment needs to be symptomatic. Patients with severe cough can take oral cough medicines, such as pulmonary cough combination and coughing tablets, and those who have more sputum that cannot be easily coughed out can take oral tranylcypromine tablets. In addition, the respiratory tract infection caused by bacterial infection should be treated with anti-inflammatory drugs, such as cephalosporin and macrolide antibiotics. If the infection is caused by a virus, antiviral treatment, such as ribavirin, is needed. For headache caused by frequent coughing, you can take relevant oral pain medications, such as ibuprofen and aminoglutethim, etc. To confirm the diagnosis, you need to go to the hospital for routine blood tests.