Liver cirrhosis is a common disease in China, and the decompensated stage is often manifested as portal hypertension: i.e., repeated esophageal and fundal varices rupture hemorrhage, intractable thoracic and abdominal water, which seriously jeopardizes the patients’ lives. In the past, conservative internal medicine and surgical shunt and disconnection could not effectively reduce portal pressure. TIPS is a new method of treating portal hypertension, which uses guide wire and catheter technology to place a metal stent between the intrahepatic portal vein and hepatic vein to establish a one-point flow channel to reduce the pressure of the portal vein, and embolize the esophageal and fundic veins that have been varicose to achieve the effect of stopping bleeding. It is suitable for patients with repeated ruptured bleeding of esophageal and fundic varices, intractable chest and ascites, and patients with unsatisfactory results of medical and surgical treatments. For patients with uncontrollable bleeding, TIPS is far better than surgical esophageal variceal ligation in terms of hemostasis and mortality, and is significantly better than endoscopic treatment and puncture ascites in preventing rebleeding and treating recalcitrant ascites. In view of its low invasiveness, no need for general anesthesia and low operating difficulty, TIPS has gradually replaced surgical shunt in the treatment of portal hypertension in Europe and the United States. After TIPS treatment, most cirrhotic patients have improved liver function, ascites reduced or disappeared, and endoscopic examination of esophagogastric fundus varices greatly reduced or disappeared.TIPS has the advantages of technically feasible, high safety, repeatable operation, obvious effect, precise efficacy, small trauma, shunt and interruption of flow. For high-risk cirrhosis with acute hemorrhage, early application of TIPS can improve the 1-year survival rate of patients and reduce the incidence of rebleeding. Since the introduction of transjugular intrahepatic portacaval shunt (TIPS), a radiologic interventional technique, into the clinic, it has become a major therapeutic option for the control of hemorrhage and refractory ascites with portal hypertension. It is particularly suitable for the treatment of patients with cirrhosis, portal hypertension, recurrent variceal bleeding due to massive portal vein thrombosis, previous splenectomy, and rebleeding after surgical porto-caval shunt. TIPS is the most difficult and risky technique in peripheral intervention. Because of the difficulty of TIPS, there are no more than 20 hospitals in the country that can perform this technique, and even less than 5 hospitals that perform it on a regular basis. At present, the number of cases completed by our center each year is among the highest in China.