What breast problems can be painful? The following: acute mastitis, some non-lactating mastitis, and most breast growths. What breast problems are not usually painful? The following: most breast cancers (early to mid-stage), breast fibroadenomas, and other breast tumors that require surgery or invasive puncture for pathological diagnosis. What does it mean? All the auxiliary examinations are to provide the doctor with a basis for diagnosis, and the doctor relies on the results of these auxiliary examinations to propose a treatment plan, but in fact at this time the doctor is guessing the nature based on experience and accumulated knowledge. The only way to determine the true nature is pathological diagnosis, which is to look at the microscopic manifestation of cells and cell masses and their surrounding interstitium (so-called tissue). Then there are only two ways to obtain cells and tissues, one is surgery and the other is puncture. So, when the doctor advises the patient to have surgery or puncture, it already means that the problem is more serious, so follow the doctor’s orders at this point!