Yue Dongsheng, Department of Lung Oncology, Tianjin Cancer Hospital: Breast cancer is a common malignant tumor in women, and the common metastatic sites include lung and bone. Once metastasis occurs in these areas, the disease is advanced and the prognosis is not too good, so be prepared. The patient showed no significant effect after chemotherapy with TP regimen, but at least the disease did not progress. This is a relatively good thing, if this after to continue chemotherapy, you can continue the original program for another two to three cycles, after this review again, if the disease no longer progresses that treatment or control the disease; if it is considered ineffective, the first-line treatment is not effective, you can replace the chemotherapy drugs, paclitaxel replaced by doxorubicin, combined with platinum. In addition, if conditions allow, you can also consider targeted drug therapy as an attempt when chemotherapy is ineffective. You’d better go to a specialized oncology hospital for consultation.