Urea nitrogen/creatinine, clinically refers to the ratio of urea nitrogen to creatinine, when the ratio is elevated generally reflects elevated urea nitrogen, may be related to high protein diet, in addition to some anisotropic hyperactivity, gastrointestinal bleeding, renal insufficiency, etc., may also appear high urea nitrogen creatinine ratio, specific treatment methods need to be treated according to the cause. 1, high protein diet: if daily like to eat a lot of lean meat, mushrooms, soy products If you like to eat a high protein diet such as lean meat, mushrooms, soy products, or take protein powder, or do a ketogenic diet, you may have a high urea nitrogen/creatinine ratio. Generally, as long as the daily protein intake is reduced, the ratio will also drop, and no special treatment is necessary; 2, gastrointestinal bleeding: high urea nitrogen/creatinine also has a certain diagnostic significance for gastrointestinal bleeding, which needs to be combined with gastroscopy and colonoscopy. Hemostatic treatment; 3. Renal insufficiency: When urea nitrogen/creatinine is high, it may suggest prerenal factors, renal factors or postrenal factors. Pre-renal factors include blood loss, fluid loss, diarrhea, heart failure, treatment requires fluid replacement, blood transfusion or correction of heart failure, etc.; renal factors include glomerulonephritis, tubular insufficiency, etc., which require hormone therapy; post-renal factors include urinary tract obstruction, tumor compression, etc., which require surgical removal of obstruction; 4, hyper-alteration: high urea nitrogen/creatinine may also indicate hyper-alteration. This process is a metabolic change in the human body and can be intervened with appropriate drugs under the guidance of a doctor. In general, when urea nitrogen/creatinine is high, it is recommended to identify the cause of the disease and treat the cause in a timely manner, taking into account the relevant imaging or test results.