Due to the complexity of the causes of urticaria, it cannot be eradicated, but the symptoms can be improved through general treatment and medication, etc. Through standardized treatment, the disease can often be well controlled. 1. General treatment: patients should actively search for the triggers, stay away from and avoid contact with the triggers. 2. Drug therapy: divided into topical drugs and systemic drug therapy. Patients can follow the doctor’s instructions to use topical glycerite lotion and other drugs with anti-itching and astringent effects. Due to the different course of the disease, it can be divided into acute and chronic, and the choice of systemic medication is also different, as follows: (1) Acute urticaria: second-generation antihistamines are preferred for anti-allergy and anti-itch treatment, such as cetirizine and loratadine; they can also be combined with vitamin C and calcium gluconate to reduce vascular permeability and reduce edema. For the more serious condition, combined with acute laryngeal edema, breathlessness, shock and other symptoms of patients, can be under the guidance of the doctor intramuscular injection of epinephrine, or tracheotomy and other rapid relief of life-threatening symptoms; and then the use of dexamethasone and other glucocorticosteroids to relieve the symptoms of edema and other symptoms, glucocorticosteroids can not be used for a long time. (2) Chronic urticaria: usually related to immunity, infection and emotion, first of all, should maintain a comfortable mood, active treatment of primary disease; preferred second-generation antihistamine drug therapy, such as loratadine, cetirizine, etc.; antihistamine drug therapy is not good, can be used in accordance with the doctor’s instructions of biologics or immunosuppressants and other therapies. Urticaria patients are advised to go to the regular hospital in time, the use of specific drugs, need to be under the guidance of a professional doctor, to avoid blind use of medication to affect health.