Invasive breast cancer is a systemic disease that requires chemotherapy for the majority of cases. Chemotherapy as a systemic treatment plays a key role in the success or failure of treatment. Chemotherapy can be done preoperatively (i.e. when the lump is not removed), so that the efficacy of chemotherapy can be determined by observing the change in the size of the lump; or after radical surgery. Whether chemotherapy is done preoperatively or postoperatively, it is recommended that chemotherapy be done in its entirety and that the scheduled chemotherapy cycle not be split up and done preoperatively or postoperatively. This means that either all chemotherapy should be given preoperatively or all chemotherapy should be given postoperatively. But these principles are not absolute, and may be handled differently for different cases. In a case like yours, you cannot say that chemotherapy is inappropriate now, it can be used as perioperative chemotherapy and surgery can be scheduled when the white blood cells return to normal, usually 21 days after chemotherapy. A complete postoperative adjuvant chemotherapy regimen will be administered after surgery.