The safety of a drug depends on what drug is given to what person, there is no absolutely safe drug, only the most suitable drug, but any drug has certain risks and side effects. For example, itraconazole, terbinafine, fluconazole and other such commonly used antifungal drugs may be relatively safe and have relatively few side effects, while ketoconazole and ashwagandha can cause a little more liver damage and are currently used less for the systematic treatment of fungal infections. Antifungal drugs are more serious to liver and kidney damage and may cause abnormal liver function, so patients need to go to the hospital for examination and need to take them under the guidance of doctors after clear fungal infection, and they need to monitor blood routine, liver function and kidney function regularly before and after medication. In addition, oral antifungal drugs at the same time to avoid drinking alcohol, so as not to increase the burden on the liver.