Auntie Zhang, 60, found blood in her stool at the beginning of this year, and thought it was hemorrhoids, so she didn’t take it seriously. When her son heard about the free colorectal cancer screening activity in the community, he persuaded Auntie Zhang to go for a checkup, but Auntie Zhang thought it was a big deal and refused to go for the checkup. Finally, after her son and daughter took turns to persuade her, Auntie Zhang went to the community health service center to fill out the “Shanghai Community Residents’ Colorectal Cancer Screening Risk Assessment Form” and had a fecal occult blood test. After the results came out, the staff of the community health service center hurriedly informed Auntie Zhang to go for a colonoscopy. It turned out that Auntie Zhang’s father died due to bowel cancer, plus Auntie Zhang had a history of constipation and bloody stools, which are all high-risk factors for bowel cancer, and most importantly, the fecal occult blood test was positive. Auntie Zhang then realized the seriousness of the problem and immediately went to the designated hospital to book a colonoscopy; the pathology of the colonoscopy suggested adenocarcinoma of the descending colon, and Auntie Zhang was hospitalized for surgery after following the doctor’s advice. After the surgery, the doctor suggested that Auntie Zhang’s brother and sister, as well as her son and daughter, go to the hospital for colonoscopy, which Auntie Zhang did not understand. The doctor explained that although most colorectal cancers are sporadic, statistics show that about 10-15% of colorectal cancers are very clearly hereditary, and people who have relatives with colorectal cancer have 3-4 times higher risk of developing this disease than ordinary people, and if there are two or more close relatives (parents or siblings) with colorectal cancer in the family, they are the high-risk group for colorectal cancer. The doctor further explained that hereditary colorectal cancer can be divided into two categories according to the presence or absence of polyposis, namely, colorectal cancer due to familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC). The former is caused by familial adenomatous polyposis cancer, which often starts in adolescence and the colon is covered with adenomas, often more than 100; the latter is an autosomal dominant familial tumor syndrome, also known as Lynch syndrome, in addition to the occurrence of colorectal cancer, the incidence of malignant tumors in the stomach, endometrium, ovaries and other parts of the body is also higher than the normal population. Auntie Zhang and her father both suffer from colorectal cancer, so her immediate family members are all high-risk groups, and even if they have no clinical symptoms now, they should go to the hospital for colorectal cancer screening, which is why the doctor suggested them to undergo colonoscopy. After Auntie Zhang’s body recovered, her son and daughter went to the hospital with her brother and sister for colonoscopy, which resulted in Auntie Zhang’s brother’s colonoscopy found ascending colon polyps with pathology suggesting adenoma; her son’s colonoscopy found descending colon polyps with pathology suggesting fractional hyperplasia. The doctor told them that the polyps found by colonoscopy had been removed and were benign, as long as they were regularly reviewed by colonoscopy. In addition, the doctor also cautioned that the diet should not be too fine, eat more coarse fiber, mixed grains and fruits and vegetables, eat less red meat, smoke and barbecue to eat less; more exercise, maintain the habit of daily bowel movements. After listening to the doctor’s words, Auntie Zhang’s family’s tense nerves finally relaxed.