Clohexine is a compound preparation of cefaclor and bromohexine hydrochloride, which is an anti-inflammatory drug. Respiratory tract infections caused by cefaclor-sensitive pathogenic bacteria with cough, coughing sputum and sticky sputum that cannot be easily coughed out are more effective and can generally be treated with clohexine, which has both an anti-inflammatory effect and a certain effect of relieving cough and resolving sputum. Cefaclor is a semi-synthetic broad-spectrum antibacterial agent, belonging to the cephalosporin class of antibiotics, which has a strong antibacterial effect on Gram-positive cocci and Gram-negative bacilli, especially on Staphylococcus aureus, Streptococcus haemolyticus and Streptococcus griseus. It has stronger effect on Escherichia coli and Klebsiella pneumoniae among Gram-negative bacilli, and also has certain antibacterial effect on Aspergillus, Salmonella spp. and Shigella spp. Katamora, Haemophilus influenzae and Neisseria gonorrhoeae are also more sensitive to this drug. Bromhexine hydrochloride can lyse and fibrillate the mucopolysaccharide in sputum, reduce the viscosity of sputum, make the sputum diluted and easy to be coughed out, and has certain effect of relieving cough and resolving sputum. If the patient is allergic to cephalosporin or bromhexine, then Krohexin should be prohibited. Some patients may experience gastrointestinal symptoms such as diarrhea, nausea, vomiting, and in a few cases, swollen lymph nodes or proteinuria after the application of Clohexine, which may disappear naturally after stopping the drug. The intestinal absorption of Clohexine is good. If patients have hyperalgesia or gastrointestinal diseases, they need to use Clohexine with caution to avoid aggravating renal damage or gastrointestinal damage.