Pediatric mesenteric lymphadenitis is usually referred to as pediatric mesenteric lymphadenitis. When suffering from pediatric mesenteric lymphadenitis, it usually hurts at night, possibly due to the diversion of the child during the day or activation of the vagus nerve at night. The lymph nodes of the mesentery are arranged along the jejunum and ileum arteries, and if they are infected by bacteria, this can lead to inflammation of the lymph nodes and cause enlargement of the lymph nodes, which often manifests itself as abdominal pain, poor nausea, vomiting, loss of appetite, abdominal masses, fever, etc. 1. Attention: children have many things to do during the day, such as playing with people, sports and other activities that attract their attention, which may excite the sympathetic nerves and make the child diverted attention, will not feel the pain caused by inflammation of the mesenteric lymph nodes, and at night when idle, can lead to concentration, it can feel pediatric mesenteric lymphadenitis is pain at night, when a hot water bag or warm towel can be applied to the abdomen, and at the same time massage, once 15 minutes, as well as to maintain adequate sleep, help to relieve symptoms; 2, vagus nerve excitement: at night when the vagus nerve is Activated, the innervated nociceptive responsiveness is increased, and thus pediatric mesenteric lymphadenitis can be felt as pain at night. The conventional treatment at this time is puncture and drainage, and you can apply non-steroidal anti-inflammatory drugs, such as ibuprofen, as prescribed by the doctor, and also give antibiotics, such as penicillin, erythromycin, or cephalosporins, such as cefixime, etc. When you have pediatric mesenteric lymphadenitis in your daily life, you need to pay attention to food safety and wash your hands before and after meals to avoid infection. It is recommended to go to the hospital promptly when symptoms are detected and to undergo standard treatment under the doctor’s orders.