Pain in the shoulder joint on the 2nd day after drinking alcohol may be due to gout, frozen shoulder, or other shoulder joint diseases. If the pain is obvious, you can give painkillers such as Lupin toine extended-release tablets to temporarily relieve the pain. Go to the orthopedic department of the hospital in time to see a doctor, who will make a preliminary judgment by combining physical examination and routine X-ray examination to determine whether there are any obvious abnormalities in the bone quality. If you are considering gout, you need to improve the uric acid measurement, and a significant increase in uric acid can be considered to be caused by gout pain, choose colchicine to reduce uric acid, also pay attention to personal habits, try to avoid drinking beer, eating seafood and animal offal, generally after 3-5 days of treatment can significantly relieve pain.