There are various treatment options for pituitary tumors, but surgery is still the main treatment. The appearance of low pituitary function after pituitary tumor surgery can be broadly classified into several categories.
1. Directly caused by surgery: Especially in large pituitary adenomas, the normal pituitary tissues have been squeezed thinly, similar to a thin layer of paper. Most of these normal pituitary tissues are easily separated from tumor tissues for good identification, but individual pituitary gland is wrapped by tumor or severely infiltrated for difficult identification, which will be easily removed together with the tumor.
Indirect reasons for surgery: As mentioned above, in large pituitary tumors, the normal pituitary gland is squeezed thin and its blood supply is affected to a certain extent.
3. Insufficient function of pituitary gland: The pituitary gland function before surgery is already insufficient or close to insufficient. Once hit by the surgery, the pituitary insufficiency is aggravated and clinical symptoms appear, and the blood test is low in endocrine hormones.
4.Post-surgery infection: Transsphenoidal surgery is a contaminated surgery with bacteria. The chance of infection after surgery is relatively high, especially for those who have cerebrospinal fluid nasal leakage after surgery. As the pituitary tissue is damaged by the invasion of bacteria and other microorganisms, and the loss of its function 5, post-surgical radiation therapy (including curcuma knife): many patients received this type of treatment again after surgery, the probability of hypopituitarism occurring in this treatment is 25-75%. According to the literature, the incidence of hypopituitarism after neuroendoscopic surgery is the lowest, while microscopic surgery or gamma knife surgery is relatively high. Therefore, it is necessary to choose surgical treatment carefully and not to listen to blind faith.
6, other causes such as erosion of local inflammatory granuloma, empty pterygoid saddle, etc.