Early stage colon cancer can be treated by endoscopic resection or surgery. In order to reduce the recurrence rate and improve the survival rate, intermediate and late stage colon cancer needs comprehensive treatment such as adjuvant chemotherapy, radiotherapy and immunotherapy, Chinese herbal medicine treatment. 1.Surgical treatment, surgical treatment is the most important means to cure colon cancer. Early detection requires timely implementation of endoscopic resection or surgical resection, and regular follow-up review after surgery, which generally does not require chemotherapy and radiotherapy, and the 5-year survival rate of early colon cancer is 80%-90%. For locally progressive colon cancer, surgery is still the only means to obtain a cure, and about 30%-50% of patients with locally progressive colon cancer can be cured through timely surgery. 2. Radiotherapy and chemotherapy treatment, progressive colon cancer needs a comprehensive treatment with surgery as the mainstay radiotherapy and chemotherapy as the supplement. For patients with difficult resection or tumor local conditions not suitable for stage I surgery, preoperative radiotherapy can shrink the tumor, increase the chance of surgical resection and reduce tumor implantation and metastasis after surgery. For high-risk stage II and stage III patients, postoperative chemotherapy can reduce the recurrence rate and improve the 5-year survival rate. For recurrent or advanced colon cancer that cannot be treated surgically, chemotherapy is an important means to control tumor progression and prolong survival. 3.Other treatments, besides surgery and radiotherapy, progressive colon cancer should be combined with other treatments, such as immunotherapy, nutritional therapy, Chinese herbal medicine, etc. Besides, maintaining a good state of mind and facing the disease positively is an important aspect to obtain good treatment effect. Early detection and early treatment of colon cancer have good effect. Even in the progressive stage of colon cancer, the chance of cure can be obtained by adopting surgery as the main comprehensive treatment method and keeping a good attitude.