Non-superficial gastritis, also called atrophic gastritis, as opposed to superficial gastritis, is a type of chronic gastritis and is a relatively common clinical condition of the digestive system. Pathologically, non-superficial gastritis is an atypical hyperplasia, which is the reason it is considered a precancerous lesion. The common cause of non-superficial gastritis is H. pylori infection. Common symptoms are pain and fullness in the upper abdomen, or symptoms such as nausea, vomiting, burping, and possibly indigestion, and in some severe cases, blood in the stool. The common treatment is medication, which can be taken under the guidance of a doctor to protect the mucous membrane, such as teprenone, aluminum thioglycollate suspension, and drugs to promote gastrointestinal peristalsis, such as domperidone tablets, metoclopramide tablets. Try to eat a light diet, do not eat spicy and cold food, and eat more food rich in vitamins and proteins. Daily attention should be paid to proper exercise to improve body immunity and promote gastrointestinal tract peristalsis. In addition, if the symptoms are not relieved or even aggravated for a longer period of time after medication and life diet adjustment, a comprehensive examination is recommended to prevent the possibility of cancer lesions.