It has been more than thirty years since the first IVF case was born in the world, and it has been more than twenty years since IVF technology (in vitro fertilization – embryo transfer technology) entered China, but the technology is still shrouded in mystery in the society, many people know little about it, and even some medical professionals do not know much about it, so here are the answers and clarifications to some IVF awareness problems and misunderstandings.
1. Repeated urine tests less than 14 days after transplantation
We do not recommend patients to repeatedly check with early pregnancy test paper. Almost all patients will buy early pregnancy test strips in pharmacies after embryo transfer in the hope of knowing whether they are pregnant early or not. Such anxiety is understandable, but there are many false positives and false negatives in the test results of early pregnancy test paper, and the accuracy is very poor, and repeated testing with unscientific methods may cause great joy and stress, which may lead to failure of pregnancy preservation.
The only accurate way is to take blood test on the 14th day after transplantation. If β-HCG level starts to rise rapidly and multiply within 2-3 days, it is generally considered to be pregnant. If beta-HCG levels do not plateau, pregnancy is not present. Some patients have a slow rise in β-HCG level, and most of these patients have a smaller chance of getting pregnant.
2. Excessive rest after transfer
Moderate rest after embryo transfer is necessary, but usually only about 2 hours of bed rest is needed to resume normal work and life. Once the embryo enters the body 2 hours later, it will be firmly adsorbed by the endometrium and will not slip off easily.
We do not recommend long bed rest, firstly, it does not help to improve the success rate, and secondly, long bed rest can easily lead to irritability, physical fatigue and even depression, which is not good for the success rate. Therefore, we recommend to resume normal activities after a short rest, but avoid strenuous activities and fatigue. There are precedents of patients who were in a particularly relaxed mood after transplantation and then went shopping everywhere, resulting in failure due to excessive fatigue.
3, medicine powder injection is better than water injection
Water injection is definitely better than powder injection, which is very different from our traditional concept. Figuratively speaking, water injection is like fresh fish, powder injection is like frozen fish, the fresh is more delicious than the frozen. In the process of freezing, the proteins are denatured, so the taste changes when it is thawed and used again. For drugs the original technology can not do freshness, so the only way to freeze drugs into powder needles, in the process of freezing and thawing to use, the quality of the drug changes, impurities increase, the activity will decline. Now the technology has been able to solve the problem of freshness, so the drugs do not need to be frozen, directly with water can be used, so as to minimize impurities and ensure the activity.
Of course, in the process of clinical use, many doctors feel that there is little difference between powder and water injection, mainly because the hormone level and disease of each patient is very different, the difference in quality between powder and water injection may not be reflected in the clinical effect and results. But from the current development trend of foreign biological drugs, powder injection is gradually withdrawing from the market, which means that the advantages of water injection in quality and the convenience of injection have indeed been more and more recognized.
4, the thicker the thickness of the endometrium, the better
It is easy to understand that if the endometrium is too thin, below 6mm, the embryo will not be easy to be bedded, but the endometrium is too thick and not easy to be bedded either. However, it is also not easy for embryos to implant if the endometrium is too thick, just like a quilt that is too thick. If the thickness of the endometrium is greater than 10mm, the chance of embryo implantation will be greatly reduced.
5.The best way to regulate the endometrium is with Chinese medicine
The best way to regulate the endometrium is to use western medicine, because the endometrium problem is mainly caused by abnormal hormone levels, so most western medicines are targeted hormones, which have a very direct effect on replenishing the endometrium. Chinese medicine also has a partly regulating effect, but the effect is not as direct as western medicine, and the composition of Chinese medicine is more complex, which can easily cause endocrine disorder, so patients are generally advised to treat with western medicine first, and then use Chinese medicine to regulate if the effect is not good. The majority of patients have achieved good results through western medicine treatment.
6, IVF charges so expensive, the success rate should be very high
The cost of IVF treatment is not cheap, but human beings are naturally animals with relatively low fertility. If both men and women are disease-free, the likelihood of pregnancy is only 10 percent per month under normal circumstances. If both men and women have a disease, the success rate is only about 1 percent. Nowadays, the single success rate through IVF technology has increased to about 40%, which is far beyond the human limit. But IVF is a science after all, and it is impossible to achieve a 100% success rate. At present, the success rate of the best foreign IVF centers can only reach 50% in general.
7. The higher the success rate of the IVF center means the higher the technical level of the center
Although the success rate is related to the level of technology, but the success rate does not represent the true level. First of all, there are many factors that affect the success rate, such as the size of the IVF center. If IVF center A is large and treats more than 1000 patients per year with a success rate of 40%, and another IVF center B treats 100 patients per year with a success rate of 50%, which one should be chosen? Theoretically, the more cycles treated, the more experienced you are and the less likely you are to make a mistake, while that small center has a high success rate, but there is a certain amount of chance, so more patients may choose center A with a 40% success rate. Another important factor that affects the success rate is the severity of the patient’s disease. Some private IVF centers refuse to treat patients with serious conditions such as premature ovarian failure in order to increase their success rate, so that their success rate will be very high, while most state-owned IVF centers do not refuse patients with serious conditions, so the success rate will be low. So don’t look at the success rate one-sidedly when choosing a center, you should consider it comprehensively. If you lack the necessary information you can post a request for help on the hope baby forum, there will be people in the industry to point out and help you avoid treatment misunderstandings.
8, if the husband has no sperm, using someone else’s sperm is not his own child
Male azoospermia is actually not uncommon in the clinic, and current technology is unable to effectively treat azoospermia. Therefore the implementation of sperm donation assisted reproduction techniques is the main means of solving fertility problems. Although it is indeed a pity to use someone else’s sperm, after all, 50% of the genes still come from the female partner; and the greatest joy of raising a child is still in the nurturing process, as long as we really invest our feelings and energy, the satisfaction we get is exactly the same. The male partner must do a good job of thinking about the female partner, because some women have difficulty accepting the reality of other people’s sperm, only the male partner can be optimistic and objective, most women can get through this hurdle very well. At the same time, the woman should also do a good job of comforting the man, usually the man’s mental pressure is difficult to release, and even some abnormal behavior, so the woman should let the man down baggage.