Breast hyperplasia occurs at the age of 35 to 50 years old, the main clinical manifestations of breast lumps, pain, lumps of different shapes, pain is mild or severe, prolonged hyperplasia can be tumor, and even develop into cancer. We have observed in the clinic that breast hyperplasia in middle-aged women is mostly related to the following three triggers: (1) emotional factors, especially long-term depression or irritability, the instability of women’s psychological traits in Chinese medicine theory is interpreted as “Liver Depression”; (2) insomnia caused by stress, irregular life, etc., especially the mental burden can trigger or aggravate breast hyperplasia; (3) the mental burden can cause breast cancer; (4) the mental stress can cause breast cancer; (5) the mental stress can cause breast cancer; (6) the mental stress can cause breast cancer. (3) Gradually fast food and westernized diets, which provide too many calories, fats and proteins, become the triggering factors for breast enlargement and even breast cancer, while traditional Chinese food, which mainly consists of beans, starch, vegetables and fruits, which are protective of the breasts, are getting farther and farther away from people. This period is the high incidence of breast cancer, so patients with breast hyperplasia at this age should be especially vigilant clinically, and systematic treatment should be adopted for hyperplastic neoplasia, cystic hyperplasia or other severe hyperplasia, and timely biopsy should be carried out on lumps suspected of having malignant possibilities. The prevention and treatment of breast hyperplasia in this period can be divided into three aspects: drug prevention and treatment, non-drug prevention and treatment, and psychological counseling.