Human papillomavirus (HPV) infection can cause a variety of diseases and can even induce malignant tumors such as cervical cancer. To date, at least a hundred types of HPV have been identified. Based on the likelihood of causing cervical cancer, in 2012 the International Agency for Research on Cancer classified them into high-risk, suspected high-risk and low-risk types. Among them, HPV type 52 is a high-risk type. However, even the high-risk type has the possibility of improvement, and its severity depends on the results of various tests. After a patient is found to have HPV-52 type, according to the current expert consensus, patients are recommended to take preventive measures through the following matters: 1. Visit a hospital gynecology department for liquid-based cytology (TCT) examination, p16INK4a and Ki-67 double-staining method (detection of viral proteins), high-risk HPV oncogene E6/E7 mRNA, multiple methylation and DNA ploidy detection. If one is positive, referral for colposcopy is recommended. Based on colposcopy, it is determined whether the patient will undergo cervical pathology biopsy. If histopathology confirms cancer or precancerous lesions, the condition is more serious and surgical treatment is required. 2. Women who are negative for all tests are recommended to undergo high-risk PCR-HPV-DNA typing retest after 1 year. If the test result is negative, it indicates that the HPV virus has been cleared. At the same time, it is recommended that the partner should also do PCR-HPV-DNA typing test. If the male partner is confirmed to have HPV infection, he should take precautionary measures to avoid HPV infection in women again as much as possible; if the test result is positive, he should continue to follow up with regular review. It should be noted that the body’s own immune mechanism can clear HPV, so the majority of genital tract HPV infection is transient, and no clinical symptoms, about 90% of HPV infection can be eliminated within 2 years. The regression time is mainly determined by the HPV type, with high-risk HPV taking 8-24 months, and only a very small number of HPV infections can become cancerous. Therefore, even if HPV high-risk type is found positive, but other tests are negative, patients do not need to worry too much, as long as they are reviewed regularly.