Preferred drug therapy.
The easiest, economical, effective, and the preferred method. 70% to 80% of patients who take regular anti-epileptic drugs are effective.
Next is comprehensive treatment.
The first treatment is surgery.
The third is surgical treatment.
Surgery should be done with caution, strict evaluation of the pros and cons, complete cutting into the epileptogenic focus, and postoperative medication; hippocampal amygdala resection for temporal lobe refractory epilepsy is effective up to 80%.
Other therapies.
Such as Gamma knife, X-knife, reflexology, Chinese herbal therapy, etc., the scope of application is not only more strict, but also less effective.
The following focus on drug therapy, for the maximum benefit of patients, based on the successful experience and historical lessons of the treatment of epilepsy in the past 100 years, experts at home and abroad carefully studied, we have further concluded the use of anti-epileptic drugs 14 word principle: early, typing, appropriate single drug, regular, long course, slow increase and decrease .
Early stage: Severe seizures can cause damage to heart, lung, liver, kidney and other organ functions, as well as traumatic brain injury, fracture, drowning and even sudden death. Loss of concentration seizures, infantile spasms, myoclonic seizures or partial motor seizures, such as multiple seizures that are not controlled, can also directly cause damage to nerve cells in the brain, making seizures more frequent and severe, and can even cause paralysis and decreased intelligence.
Typing.
There are dozens of antiepileptic drugs, each with its own advantages and disadvantages, a certain range of application, how to choose the drug? Clinical studies have found that drug response is highly dependent on the type of seizure. For example, phenytoin sodium is not suitable for infants and young children, carbamazepine and valproic acid are often effective for partial seizures, valproic acid is often effective for aphasic seizures, infantile spasms require treatment with corticotropin (ACTH), nitrazepam, clonazepam or valproic acid, and valium drugs are commonly used to rescue persistent epilepsy. However, this is by no means an unchangeable formula, but rather a general rule derived from the summary of a large number of clinical medications, which sometimes need to be replaced or combined with other antiepileptic drugs. In addition, the patient’s age, liver and kidney condition should be taken into consideration when selecting drugs, for example, it is not easy to use phenytoin sodium for a long time in young children, and valproic acid is not used when liver dysfunction is present.
Single drug is preferred.
When one drug can completely control the seizure, there is no need to add a second one at all. Clinical studies have found that the majority of patients (70% to 80%) can have complete seizure control with one antiepileptic drug and do not need to take other drugs at all. Only those patients whose seizures cannot be controlled after regular and systematic monotherapy should be considered for additional medications. The addition of drugs should be done under the guidance of a specialist, because there are many disadvantages when adding a second drug: if toxic side effects occur, it is not easy to figure out which drug is the cause, so it is difficult to determine which drug to stop; the two drugs may interact with each other to reduce the efficacy or increase the poisoning; the combination of multiple drugs increases the patient’s trouble and economic burden of taking medication, and it is not easy to adhere to the medication for a long time. Therefore, blindly treating 2 or more drugs at the same time will not only fail to be effective, but also aggravate the disease, and the situation of 1 + 1 < 1 will occur.
Regular medication.
Seizures cannot be predicted, and if the amount of medication in the body is not enough, the seizures may be repeated and cannot be controlled; sudden discontinuation of medication will break the adaptation state between the medication and the body, making the seizures worse. The interval between medications should be decided according to the characteristics of the drug, such as phenobarbital and other drugs with slow metabolism in the body, 2 times a day is enough, however, ordinary carbamazepine tablets are metabolized quickly in the body and eaten 3 times a day in order to play a stable role.
Long course.
After the seizures are controlled by the drug, the drug should not be stopped immediately, but should be insisted on regular maintenance doses for 2 to 5 years, and if there are still no seizures, then consider slow reduction of the drug. The discontinuation process takes about six months to a year. If you stop the medication too early or too soon, the epilepsy is likely to recur.
Slow increase and decrease.
The ideal goal is to use the smallest possible dose to completely control seizures without toxic side effects. Of course, for patients with frequent seizures, the dose should be increased as soon as possible to control seizures without serious side effects. When a drug has reached its maximum dose and stable blood concentration, but the condition still does not improve, you should consider adding or switching to another antiepileptic drug. If you have a problem with the first drug, you should consider gradually reducing the first drug when the second drug has the best effect.
The first one is the first one, and the second one is the second one. In fact, many experts have carefully studied these “earth, single, experimental” prescriptions, and have not found a prescription that has the same good efficacy as the commonly used western drugs. The actual fact is that you will be able to get a lot more than just a few of these. Even if long-term medication is ineffective, you should not give up regular medication by believing in “earth, single, and experimental” prescriptions. In the late 1940s and early 1970s, many places in China were treated for epilepsy by “cutting”, “burying” and “burying”, but later, because these treatments were not effective, people gradually gave up. The people gradually gave up. However, in recent years, some people, in the name of “traditional Chinese medicine”, have been wildly promoting “cut and cure”, “buried thread” and “buried medicine” through “sea, land and air” media. “The purpose of this is to cheat money. The actual fact is that you will be able to get a lot more than just a few of the most popular and most popular items.