Medication points for physicians 1. First-line therapeutic agents for Parkinson’s disease include levodopa, non-ergot dopamine receptor agonists, and B-type monoamine oxidase inhibitors. 2. Consider initiating levodopa therapy in all (except younger) patients, especially those with severe motor symptoms (due to their excellent performance in terms of motor symptom benefit) or cognitive impairment. 3. Monitor for motor system complications (dyskinesia, motor symptom fluctuations), impulsive behavior and adjust the dose accordingly. 4. Do not stop the drug abruptly, which may cause malignant hyperthermia (Parkinson’s hyperthermia syndrome). Some reminders for people with Parkinson’s disease and caregivers 1. Do not stop the medication suddenly, as this can have life-threatening consequences; 2. Inform your doctor if you experience severe drowsiness while using Parkinson’s disease medication; avoid driving and heavy machinery if your symptoms are very severe; 3. 4. If you notice any change in impulsive behavior after taking the medication, such as hypersexuality, gambling impulse, shopping impulse and overeating, please report to the doctor.