Ultra-Minimally Invasive Liquid Needle Knife Therapy is a combination of “Green Therapy” and “Holistic Therapy”, which not only has the combined effects of needles and knives, but also has the effects of liquid and ozone needle knives. It is a safe, fast-acting, painless, minimally invasive needle method that intervenes between surgical and non-surgical methods of closed loosening. Ultra-minimally invasive liquid needle knife is a combination of: needle knife, liquid and ozone as a whole. The therapy rapidly stabs the liquid needle knife into the patient’s painful joints at acupoints or pain points. It takes only a few seconds to stab the needle knife into the lesion, generating mechanical stimulation, loosening the adhesions, contractures, and scarring of the soft tissues, improving the periarticular blood flow, promoting blood return, and restoring the balance of the periarticular soft tissue mechanics. The indications for “Liquid Needle Knife Therapy” are mainly soft tissue injury lesions and osteoarthritic lesions. For example, cervical spondylosis, lumbar intervertebral disc herniation, knee osteoarthritis, tenosynovitis, heel pain and other diseases.