Reflux esophagitis is an inflammatory esophageal lesion caused by the reflux of gastric and duodenal contents into the esophagus, which endoscopically manifests as a breakdown of the esophageal mucosa, i.e. esophageal erosion and/or esophageal ulcer. Reflux esophagitis can occur in people of any age, with the incidence increasing with age in adults. Middle-aged and elderly people, obese people, smokers, alcohol drinkers and people under stress are at high risk of reflux esophagitis, which has clinical manifestations such as retrosternal pain, acid reflux, burning sensation, nausea and vomiting. Reflux esophagitis can cause esophageal stricture. This is caused by scarring of the esophageal mucosa and contracture of the scarred area, resulting in narrowing of the lumen of the esophagus. Patients with esophageal stricture may have difficulty swallowing, which may start intermittently and may become more pronounced as the disease progresses. When esophageal mucosa erosion damages the walls of the blood vessels, it can cause bleeding. If the bleeding is heavy, the patient may vomit blood. Some patients may develop lesions in the mucosa of the lower esophagus, which is called Barrett’s esophagus, a complication of GERD and a recognized precancerous lesion, i.e., a high-risk factor for esophageal cancer.