Gastrointestinal tumors are highly prevalent gastrointestinal malignancies. Like other solid tumors, the main treatments for gastrointestinal tumors include surgery and radiotherapy. From the consultation situation, about more than half of the patients are already in the middle or late stage when gastrointestinal tumors are detected, and radical surgery cannot be performed or surgery cannot completely remove the cancer cells. Adjuvant treatments such as radiotherapy and chemotherapy can make up for the limitations of surgery, and chemotherapy becomes an indispensable part of gastrointestinal tumor treatment. And due to the continuous development of newer drugs, the effectiveness of chemotherapy for gastrointestinal tumors has been greatly improved. How to develop a suitable chemotherapy regimen for patients? Chemotherapy for gastrointestinal tract tumors is slightly lower in dose intensity compared to other malignancies (e.g. leukemia, breast cancer), and most chemotherapy regimens in which fluorouracil is administered continuously intravenously for 24 hours. Many patients are concerned whether the toxic side effects from such continuous dosing will be intolerable. In fact, toxic side effects can be minimized and somewhat prevented by doing enough work prior to chemotherapy. Doctors first generally assess the characteristics of the patient’s gastrointestinal tumor and whether it is sensitive to chemotherapy. Then, the patient’s liver and kidney function and blood routine are examined to see whether the patient is anemic and whether the white blood cell count is normal. In addition, the patient’s tolerance to chemotherapy will be determined based on diet and exercise. The doctor will know what kind of toxic side effects the chemotherapy drug will have, and will take precautions in advance. After the first course of treatment, the doctor will adjust the regimen and dose according to the patient’s response to chemotherapy in a timely manner. Chemotherapy must be “time-limited” Generally, chemotherapy can be administered 3-4 weeks after surgery. Doctors will develop chemotherapy regimens according to the patient’s physical condition, so there is no need to worry too much about delaying the best adjuvant treatment. In addition, in the process of chemotherapy, the administration of drugs should be timely and on time, generally 2-4 weeks for a course of treatment, some patients have a course of treatment after a long delay to do the second course, which will affect the effectiveness of treatment. Some tests during chemotherapy must also be performed in a timely manner. Every 1-2 courses of treatment, electrocardiograms and liver function tests should be done, and routine blood tests should be performed once a week, and if the white blood cells drop, they should be dealt with promptly, otherwise the subsequent chemotherapy will be affected. Patients should choose experienced specialists for chemotherapy, and the first chemotherapy must be followed up closely. The whole process of chemotherapy should preferably be carried out under the guidance of one doctor, so that the doctor can grasp the patient’s situation more completely and make appropriate dose adjustment and treatment of adverse reactions. Adverse reactions of chemotherapy for gastrointestinal tumors Chemotherapeutic drugs have the strongest killing effect on fast-growing cells, which inevitably kill some fast-growing cells in our body, such as gastrointestinal epithelial cells, hair follicle cells, and hematopoietic cells. Therefore, vomiting, diarrhea, hair loss, anemia and low resistance are the most common effects after chemotherapy with traditional cytotoxic chemotherapy drugs. Common side effects: 1. Nausea and vomiting, general weakness: This is a common reaction after chemotherapy, but generally within the patient’s tolerance range. Some chemotherapy drugs with strong emetic properties are usually given to patients before chemotherapy with central antiemetic drugs, which are generally tolerated by many patients. 2. Numbness and desquamation of hands and feet: Oxaliplatin and Siroda, commonly used drugs in chemotherapy for gastrointestinal tumors, can cause numbness and desquamation of hands and feet, at this time, attention should be paid to hand and foot insulation and vitamin supplementation. 3. Anemia and bone marrow suppression: Most chemotherapy drugs can cause bone marrow suppression, which is manifested by the decrease of white blood cells and platelets, or even the decrease of red fine chest and hemoglobin. Individual differences, bleeding serious myelosuppression should be adjusted immediately, or even suspend treatment. Diet and exercise during chemotherapy Stomach cancer patients often lose their appetite during chemotherapy and do not want to eat anything or dare not eat anything. In fact, a certain amount of food intake should be ensured during chemotherapy to ensure basic energy. Eat something light, eat less and more meals, do not be overly full, usually six or seven minutes full is enough. Drink more water to facilitate the excretion of metabolites. After chemotherapy, nutrition should be gradually supplemented with a balanced intake of protein, vitamins and trace elements, choosing different kinds of food. Patients should also do some activities that they can do, take care of themselves, and strengthen communication with family and friends. In addition, family members should also pay attention to the patient’s diet during chemotherapy, and give the patient food that is easy to digest and at the right temperature. Particular attention should be paid to some chemotherapy drugs (such as oxaliplatin) requiring patients to avoid all cold contact. The patient’s room should be ventilated and ventilated at all times to keep the air fresh and circulating. Treat with a normal heart and the results will often be better.