Early stage of chronic kidney disease may be asymptomatic, or the symptoms are very inconspicuous, which is related to the strong compensatory function of the kidneys. Even if the loss of renal function is more than 50%, some patients with chronic kidney disease may not have any obvious symptomatic manifestations, so it is necessary to pay attention to observation in our daily life and don’t ignore the warning signals given by the body. When certain symptoms appear, please consult a doctor in time …… 1, change in urine volume Normal people urinate 1,000 to 2,000 ml per day and night, a significant increase or decrease or nocturnal urination, etc., may indicate that the kidneys have problems. 2.Color change of urine If the color of urine suddenly appears red, tea color, or there are bubbles in the urine that are not easy to dissipate, you should be alert to the possibility of kidney disease, and go to the hospital in time for a simple routine urine test, and it is very important to get the doctor’s help and guidance. 3.Other physical symptoms Anorexia, nausea, vomiting, diarrhea, etc. Similar problems often occur when the excretory function of kidney decreases. Longer mental depression, fatigue, dizziness, memory loss, insomnia, etc., be alert to exclude kidney function problems, affecting the nervous and endocrine system. Depressible swelling, i.e., generally appears around the eyes or in the hands and ankles. When pressed with a finger, a depression appears at the pressed area, and when the finger is lifted, the depression recovers slowly, which is a common cause of decreased excretory and filtration functions of the kidneys. Anemia, dry, flaky, shapeless and itchy skin are similar symptoms when kidney disease affects the blood system. The onset or worsening of symptoms such as high blood pressure, blurred vision, vision loss, and cardiac arrhythmia should alert or rule out changes caused by chronic kidney disease. High blood pressure, diabetes, recurrent respiratory infections, a family history of chronic kidney disease, obesity, the elderly, and those who regularly take a variety of medications may be at high risk for chronic kidney disease and need to be vigilant.