Adults with fever of 39℃ are beyond the range of self-regulation of the body and usually cannot reduce the fever by themselves. The most commonly used antipyretic drugs are acetaminophen (paracetamol), ibuprofen, etc. Most of them take effect within 2 hours, and the average time to take effect is about 1 hour after taking the drug. Generally every 6-8 hours to take 1, the shortest interval is 4 hours, not more than 4 times a day. Second, physical cooling 1, ice: the use of ice bags, ice bags placed on the head, armpits and groin; 2, alcohol rubbing: patients take a supine position, from the neck down along the outside of the arm to the back of the hand, and then a small towel, from the armpit along the inside of the arm to the palm of the hand, wipe the opposite side in the same way; then, from the groin through the leg wipe to the foot. Then, let the patient take the side position, starting from the back of the neck, wipe the whole back from top to bottom. If the adult fever has reached 39℃, the cause should be actively searched for and treated. If the patient has infectious fever, appropriate medication should be selected according to the source of infection; if the fever is caused by dehydration, rehydration treatment should be actively carried out.