One of the most commonly damaged target organs of hypertension is the heart, which can cause left ventricular hypertrophy, coronary atherosclerosis, arrhythmias and heart failure. Hypertension can exacerbate the development of coronary heart disease by increasing myocardial oxygen consumption, and effective blood pressure lowering can significantly reduce the incidence of cardiovascular events in coronary heart disease. Some studies have shown that the mortality rate of coronary heart disease is 0.32% in those with normal blood pressure, but 5 times higher in those with hypertension. Although hypertension is an important risk factor for coronary heart disease, the benefit of lowering blood pressure for coronary heart disease is much less than that for stroke. The results of the ideal treatment of hypertension (HOT) revealed that the risk rate of death from coronary heart disease was lowest with an average blood pressure of 138.5/82.6 mmHg on antihypertensive therapy. The explanation for this result is that the coronary blood supply to the heart is dependent on diastolic blood pressure, and the incidence of myocardial infarction is significantly higher for both diastolic blood pressure <70 mmHg and diastolic blood pressure >90 mmHg. Therefore, the target blood pressure for patients with coronary heart disease should be <140/90mmHg, and it is safe and effective to lower it to 120-130/70-80mmHg. What antihypertensive drugs are used for coronary heart disease? It is generally believed that the degree of spokes for lowering blood pressure is more important than the choice of the drug. First-line drugs can be angiotensin-converting enzyme inhibitors (ACEI) or angiotensin II receptor antagonists (ARB), calcium antagonists (CCB) or thiazide diuretics, and if the blood pressure is greater than the target blood pressure of 20/10 mmHg, two different antihypertensive drugs should be used at the beginning. In those with a previous history of myocardial infarction or with angina pectoris or with left heart insufficiency or heart failure, antihypertensive measures should include beta blockers (short-acting beta1 selective-release ones without intrinsic sympathetic activity) at the outset. In patients with heart failure, β-blockers should be started only after hemodynamic stabilization and non-dihydropyridine calcium antagonists such as isoptin and thiazepam should be avoided. In coronary artery disease with left heart insufficiency or heart failure, aldosterone antagonists are effective, and potassium and creatinine values should be monitored. In June 2007, the American College of Cardiology Hypertension Research Society, Clinical Cardiology and Epidemiology and Prevention Society published "Hypertension Treatment to Prevent Ischemic Heart Disease", it is pointed out that: (1) for patients with coronary heart disease or coronary heart disease and other critical conditions, the standard blood pressure should be <130/80mmHg, and if there is heart failure, it can be considered to lower to <120/80mmHg; (2) for patients with existing coronary heart disease (2) For patients with existing coronary artery disease, the blood pressure should be lowered slowly, and for elderly people (>60 years old) with diabetes mellitus and other critical conditions such as coronary artery disease, the diastolic blood pressure should not be <60mmHg; (3) Although beta blockers are not used for primary prevention, they are still the main medication for patients with existing coronary artery disease. This document provides more comprehensive guidance on the principles of using antihypertensive drugs for coronary artery disease.