Urinary frequency, urinary urgency and stinging pain are commonly associated with urinary tract infections and urinary stones in clinical practice. Normal adults urinate 4-6 times during the day and 0-2 times at night, the increase in the number of urination per unit of time is urinary frequency; urinary urgency refers to the emergence of the urge to urinate that can not wait to need to urinate, difficult to control, urinary stabbing pain refers to the pain or burning sensation in the suprapubic area, perineum and urethra when urinating, the three manifestations together called bladder irritation signs. Clinical common in the following diseases: 1. urinary tract infection: 1. upper urinary tract infection: such as acute pyelonephritis, renal pus, etc., caused by upstream infection of pyelonephritis can mostly appear bladder irritation signs in the early stage, bloodstream infection often first appear high fever, followed by bladder irritation signs, may also appear fever, back pain and other symptoms, often accompanied by cystitis. Patients with renal pus accumulation commonly have clinical symptoms such as chills, high fever, pain in the lumbar region and a lump is seen. If the urinary tract is incompletely obstructed and pus is discharged into the bladder, bladder irritation signs will appear; 2. Lower urinary tract infection: bladder irritation signs are the main clinical manifestations, such as acute and chronic bacterial cystitis, often accompanied by fever and burning sensation in the urethra, which can affect urination due to pain. May be accompanied by urethritis, acute infection may have swollen inguinal lymph nodes on both sides, urethral orifice mucosa redness, itching, tingling, etc. Upper urinary tract stones: 1. Upper urinary tract stones: kidney stones and ureteral stones can often be accompanied by back pain and bladder irritation when the stones are infected or in the ureteral bladder wall; 2. Lower urinary tract stones: bladder stones have bladder irritation, with typical symptoms of sudden interruption of urination and pain radiating to the distal urethra and the head of the male penis. Typical symptoms of urethral stones are difficulty in urination, dribbling urination, often accompanied by painful urination, and easy to develop infection. Third, other: such as prostatitis, patients can be accompanied by frequent urination, urinary urgency, urinary stabbing pain performance, the specific cause is still unclear, the clinical most believe that bacteria, viruses and other microbial infections caused.