Parkinson’s disease is a common neurological disorder that occurs mainly in middle-aged and elderly people, mostly after the age of 60, but in recent years it has gradually become younger, with the youngest patients seen in their 30s. Young and middle-aged Parkinson’s disease is insidious and can be easily misdiagnosed. It usually starts with a resting tremor or stiffness in one limb, dragging when walking, and slowly worsens over a number of years before progressing to the other limb. The symptoms progress to the other limb over a number of years. Myotonia increases and the swing of the upper limb decreases when walking, until in the middle and late stages of the disease, the four main symptoms of tremor, stiffness, bradykinesia and abnormal posture may appear. In the early stage of young and middle-aged Parkinson’s disease, if the symptoms are not serious or obvious and do not affect work and life, clinical observation can be carried out according to medical advice, and no treatment or application of neurophilic nutrients for the time being; if work and life are affected to a certain extent, medication should be taken, and dopamine agonists, monoamine oxidase inhibitors and amantadine should be chosen, while levodopa preparations should not be used as much as possible. The most effective “honeymoon period” for levodopa treatment is only about 5 years, after which not only the dose increases and the efficacy decreases, but also the body will After the “honeymoon period”, not only the dose increases and the efficacy decreases, but also the body may experience shaking and hand-movement symptoms, the idiosyncratic phenomenon of drug effects coming and going, and other adverse effects of movement disorders. In the middle and late stages, when the symptoms are more pronounced, the medication should be administered rationally, but the dose titration principle should also be observed. Brain pacemaker therapy for Parkinson’s disease is relatively mature. The period of brain pacemaker therapy for Parkinson’s disease should not be too late, and brain pacemaker surgery should be considered if drug therapy is past the honeymoon period, when efficacy declines and adverse reactions occur.