In laboratory cell studies and studies in mice, it was found that high doses of vitamin C could enhance the anti-cancer effects of chemotherapy. In the 1970s, chemist Linus Pauling reported that intravenous administration of vitamin C could be an effective treatment for cancer. However, the same effect could not be achieved with oral vitamin C. This is thought to be due to the fact that if vitamin C is taken orally, it is rapidly excreted by the body. Scientists at Kansas State University say that the body absorbs the injected vitamin C and that it works in the body to kill tumor cells, while doing no harm to normal cells. In the laboratory, researchers injected vitamin C into human ovarian cancer cells, mice, and patients with advanced ovarian cancer. In the end, it was found that ovarian cancer cells were very sensitive to vitamin C treatment, while they were harmless to normal cells. Also, in the mouse study, it was found that sequential vitamin C treatment with standard chemotherapy drugs slowed the growth of tumors. Also vitamin C can reduce the adverse effects of chemotherapy.