What is an invasive test? Invasive tests are used to obtain bone marrow, cerebrospinal fluid, thoracoabdominal fluid and some tissue cells by using some invasive means (such as bone puncture, lumbar puncture, thoracic and abdominal puncture, needle aspiration biopsy, excisional examination, etc.) to help the doctor make a diagnosis through visual observation, laboratory tests and histological examination during the consultation. To put it in layman’s terms, you may have to bleed a little and go through the skin or muscles or internal organs to extract diseased tissue for the necessary tests. Why are invasive tests performed? Invasive tests are commonly used in the medical diagnosis process today. Doctors often use invasive tests as a key to unlock the door to diagnosis when many conventional methods fail to make a clear diagnosis. Many people refuse these tests due to lack of knowledge, especially for pediatric patients, and parents refuse these tests due to concerns about pain, adverse reactions or danger, not knowing that this often prevents patients from receiving timely and correct diagnosis and treatment. For many tumors, these invasive tests are very necessary. For example, when leukemia or lymphoma is suspected, clear diagnosis and staging can often be made through bone marrow aspiration smear, which can lead to early detection and diagnosis before symptoms of the primary tumor appear; direct biopsy of the tumor site can clarify the nature of the tumor, which is very important for deciding further treatment plan. There was a patient who was hospitalized with cough, fever and swollen lymph nodes, because the patient’s family was reluctant to accept lymph node biopsy in the early stage, but could only be treated as general lung infection, and later agreed to lymph node biopsy only when the result was not satisfactory. The family regretted that if the diagnosis had been known earlier, the patient might have had some chance of survival, but it was too late to regret. The risk of invasive tests is not high: Many patients are afraid when they hear about invasive tests and are reluctant to undergo them for fear of suffering. As for other tests such as bone puncture, lumbar puncture and chest puncture, they are seldom seen and may be misunderstood because they are not understood. On the contrary, because of the patient’s own nervousness, the examination process may become complicated and undesirable accidents may occur, so patients and their families should not have prejudice against these examinations and should accept them with a normal mind. Of course, invasive examinations may also have certain risks, otherwise, it would not be called by this name, the specific situation is related to the examination items, such as redness, swelling, pain, infection and general discomfort at the puncture site, but usually do not cause serious complications, doctors will explain in detail to patients and families about the need for the examination and possible risks before the examination, compared to the possible delay in diagnosis and treatment Compared to the possible delay in diagnosis and treatment, the risk of invasive tests is still very small. Families and patients should weigh the pros and cons and should not refuse invasive tests for unnecessary concerns, which may delay diagnosis and treatment and cause lifelong regrets. However, invasive tests may have limitations like other tests, such as the need for multiple tests at different times due to changes in the condition, the inability to make a clear diagnosis or exclude the condition after the test, or the inability to complete the test due to the lesion or the patient’s health. At this time, patients and families need to be more understanding and cooperative, one-sided pursuit of perfection and blame may often tie the hands of doctors.