In modern society, cancer has become a disease with a very high mortality rate, especially breast cancer in women, women, having breast cancer is not scary, what is scary is that it leads to breast cancer metastasis. First of all, the most common metastatic site of breast cancer is the lung, what are the parts to which breast cancer usually metastasizes? Lung metastasis: 1. Lung metastasis is usually through bloodstream metastasis, lymphatic tract metastasis or direct invasion. It is the most frequent distant metastasis of breast cancer. Seventy-five percent of patients with recurrent breast cancer will have lung metastasis. 2.Breast cancer varies according to the site of metastasis. Common symptoms include coughing up sputum, coughing, coughing up blood, difficulty breathing, and coupled with fever symptoms. Where does breast cancer usually metastasize to? If breast cancer metastases occur in the interstitial lung, early, isolated nodules are often asymptomatic, but can be detected by imaging. If the metastases are located in the bronchial lining, coughing symptoms are apparent and obstructive pneumonia or atelectasis may occur. If cancerous lymphangitis of the lung is present, dyspnea, cough with sputum, purple give and chest pain, and there may be diminished lung breath sounds. 3.If mediastinal metastasis occurs at the same time, phonation, superior vena cava compression syndrome, septal paralysis and compression symptoms of esophageal trachea may appear. Occasionally, the tumor causes acute pulmonary embolism, which manifests as progressive dyspnea. Bone metastasis: 1. Breast cancer mainly metastasizes in the form of hematogenous dissemination, and 60% of patients with uncured breast cancer will have bone metastasis. The thoracolumbar vertebrae and pelvis are most likely to be metastasized, with the incidence rate of 64.7% and 41.2%, followed by the ribs (which are adjacent to the cancer foci), skin bone, femur and skull, and the sternum has the lowest metastasis rate of about 3.5%, and clinically multiple bone metastases are more common than single ones. 2. Mild, intermittent bone pain appears in the early stage of metastasis, which gradually develops into persistent bone pain with progressive increase and pressure pain, and if the vertebral body is involved, pressure pain and percussion pain of the spinal spine can appear. The pain can be fixed or irregular, especially at night, and the pain is varied. The pain causes muscle tension and restriction of joint movement, resulting in a passive position. If the location of the bone metastases is superficial, or if the bone swells and deforms over time, local swelling may occur. 3. Pathological fracture occurs. Since breast cancer is easy to develop bone metastasis, some patients even have pathological fracture as the first symptom of breast cancer in the past. These pathological fractures can occur on their own or under the effect of slight external force, and the symptoms and signs are different depending on the location. Pathological fracture of vertebrae manifests as cone deformation and collapse, which can lead to symptoms of spinal cord compression. Initially, the symptoms are nerve root pain and sensory impairment, and when the lesion progresses to partial spinal cord compression, hemisection syndrome can occur, and when it enters the stage of complete spinal cord compression, paraplegia occurs. Liver metastasis: 1. The liver is one of the common metastatic sites of breast cancer, which often leads to failure of breast cancer treatment. About 60% of patients with untreated breast cancer will develop liver metastases. The main routes of liver metastasis are hematogenous metastasis and lymphatic metastasis, of which hematogenous metastasis is the main one. The first place in the hematologic dissemination of breast cancer is lung, then bone, and the third place is liver. The clinical manifestations of breast cancer liver metastasis are similar to those of primary liver cancer. In the early stage of metastasis, there is no symptom, but later there will be distension and discomfort in the upper abdomen or liver area, followed by abdominal distension, jaundice, loss of appetite, weakness, weight loss, severe pain in the liver area, fever, etc. 3. On physical signs, hepatomegaly can be seen, and even a lump with uneven surface and edges of the liver, ascites and xanthogranuloma can be withheld. Brain metastasis: 1. Brain metastasis of breast cancer occurs mainly through bloodstream metastasis, and the incidence is about 15% in patients with untreated breast cancer. Brain metastasis is a fatal complication of breast cancer and is one of the main reasons for treatment failure. The main clinical manifestations include cerebral edema and intracranial hypertension, neurological symptoms, such as headache, vomiting, loss of vision, convulsions, impaired limb movement and even coma, and weakening or disappearance of physiological reflexes of the nervous system and elicitation of pathological reflexes. Pleural metastasis: Pleural metastasis can occur through hematologic or local invasion of breast cancer, or pulmonary metastasis can cause pleural metastasis after penetrating into the pleural cavity, usually patients have symptoms of chest tightness, chest pain, shortness of breath and cough. Pleural effusion signs can be seen on physical examination, and bloody pleural fluid can be extracted by puncture. Multiple metastases in late stage of breast cancer: Patients with advanced breast cancer have multiple metastases throughout the body, and their health condition deteriorates rapidly with cachexia, progressive aggravation of mental depression, depression, indifferent expression, loss of appetite, emaciation, anemia, severe and stubborn cancer pain, and elevated body temperature. Breast cancer can metastasize to other places through bloodstream metastasis, lymphatic tract metastasis or direct invasion. If you have breast cancer, be careful to prevent metastasis, which can cause irreparable damage.