Chronic non-atrophic gastritis is not a fatal disease, nor is it a malignant lesion, and under normal circumstances the disease itself does not affect life expectancy. Chronic non-atrophic gastritis is commonly referred to as chronic superficial gastritis. Atrophic and non-atrophic are a conclusion of the disease after the classification of chronic gastritis based on the changes of the gastric mucosa seen under gastroscopy and the pathological diagnosis of the gastric mucosa. Non-atrophic gastritis is divided into non-atrophic sinusitis and non-atrophic total gastritis depending on the location of the endoscopic inflammatory lesions. Non-atrophic sinusitis mainly presents with marked inflammation of the gastric sinus and mild or no inflammation can be seen in the body of the stomach. Non-atrophic gastritis suggests significant inflammation of the entire gastric mucosa, with similar degrees of mucosal inflammation in the sinus and body of the stomach, with no significant differences. The main clinical cause of chronic non-atrophic gastritis is H. pylori infection. In addition, it can also be caused by bile reflux and excessive alcohol consumption. Most patients can have no obvious clinical symptoms, while others present with abdominal pain, bloating, postprandial fullness, belching, acid reflux, and decreased appetite. However, these symptoms are not specific, and a definitive diagnosis needs to be made with the help of gastroscopy and histopathological examination of the gastric mucosa. If the disease is recurrent or the symptoms persist for a long time, it is recommended to visit a regular hospital for active standardized treatment. The treatment of the disease mainly includes the eradication of H. pylori, the inhibition of gastric acid secretion, the protection of gastric mucosa and the promotion of gastric motility. The treatment of this disease should follow the principle of individualization, and the treatment plan should be selected according to the different conditions and causes of the patient. Chronic non-atrophic gastritis will not affect the normal life expectancy after active treatment and dietary modification. However, if treatment is not actively given it may also develop into atrophic gastritis, intestinal chemosis, heterogeneous hyperplasia, etc., which may eventually develop into gastric cancer, and such development will affect life expectancy. Treatment of chronic non-atrophic gastritis needs to be combined with a good diet and a healthy lifestyle, and regular review.