After vaccination, some patients are sensitive and may have a series of reactions, which are usually divided into local reactions or systemic reactions, with the following common manifestations: 1. Local reactions: After vaccination with the new crown vaccine, some patients may have local discomfort reactions such as slight pain, redness, swelling and papules at the injection site, and the symptoms are mild and can usually heal by themselves after 2-3 days. The local area should be kept clean and dry, avoid scratching with hands, and for patients with local redness, swelling and itching, alcohol disinfection can be given appropriately. However, patients with severe redness, itching and pain should seek medical treatment promptly. 2. Systemic reactions: Some patients may also experience nausea, fever, headache, muscle pain, diarrhea and even systemic allergic reactions after vaccination with the new crown vaccine due to individual differences; in serious cases, please seek medical treatment promptly and report the relevant situation to the vaccination unit. The above-mentioned reactions do not occur in all vaccinated persons, and are only reactions under individual differences. Therefore, for patients who have the need for vaccination, it is recommended to consult at the vaccination site according to their actual situation, and the relevant staff will provide detailed answers.