Patients with hypertension who take antihypertensive drugs often cause symptoms of panic, and there are several clinical reasons for this: 1. Patients with hypertension who take short-acting antihypertensive drugs will make their blood pressure fall too fast, and if this causes cerebrovascular insufficiency of perfusion, it will activate the carotid sinus pressure receptors, and after the carotid sinus pressure receptors are activated, it will cause sympathetic excitation leading to an increased heart rate and symptoms of panic. 2. There are five major types of antihypertensive drugs commonly used in clinical practice, including diuretics, beta-blockers, calcium antagonists, angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists, of which calcium antagonists often have sympathomimetic activity, causing hypertensive patients to experience an increased heart rate. In addition, diuretics cause electrolyte disturbances, often causing palpitations and increased heart rate in patients with hypertension.