We often encounter patients who come to our urology clinics with the problem of premature ejaculation, but due to misinformation from the Internet, television, newspapers and other media, patients often self-diagnose themselves as having prostatitis, believing that their premature ejaculation is the result of prostatitis. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. The actual fact is that you will be able to get a lot more than just a few of these, and you will be able to get a lot more than just a few of these. In contrast, there is no exact definition of premature ejaculation. From an evidence-based perspective, the definition of premature ejaculation includes a short duration of ejaculation, an uncontrollable ejaculatory condition, and the presence of resulting personal psychiatric problems such as distress, apprehension, frustration, and/or avoidance of sexual activity, among others. Premature ejaculation may be the result of somatic diseases or neurophysiological disorders, and prostatitis may also be one of the causes of premature ejaculation, in the sense that there is a degree of correlation between prostatitis and premature ejaculation. At the same time, a series of unscientific and unregulated treatment activities carried out by patients due to premature ejaculation problems, such as some irregular treatments via the rectum often lead to the occurrence of prostatitis. The incidence of prostatitis is relatively high, with data showing that more than half of men will be affected by prostatitis at some point in their lives, and patients with prostatitis account for about 1/4-1/3 of urology clinics. The causes of its onset are many, including pathogenic infections, urinary dysfunction, psychological and neuroendocrine factors, etc. The triggering factors include smoking, drinking alcohol, eating spicy foods, and inappropriate sexual activity. The reason for this is still unclear. The psychological abnormalities caused by prostatitis may also be one of the causes of premature ejaculation. The diagnosis of chronic prostatitis is only an exclusionary diagnosis due to the lack of objective and specific diagnostic basis. After excluding pain and discomfort in the pelvic region caused by other diseases and abnormalities related to urination, the diagnosis is mainly based on the diagnostic symptom score (CPSI) and judging its severity. The diagnosis of premature ejaculation is based on the patient’s complaints and the PEDT, IELT, and IIEF-5 scales. It is not uncommon for the two conditions to be combined clinically, but this does not mean that there is some degree of causality between the two. The goal of treatment for chronic prostatitis is to relieve pain, improve urinary symptoms and improve quality of life, and the evaluation of efficacy is based on symptom improvement, generally using a-blockers, non-steroidal anti-inflammatory analgesics, herbal botanicals, M-blockers and so on, such as co-infection plus the use of In patients with depression and anxiety, antidepressants and anti-anxiety drugs should be added to improve psychological disorders and relieve symptoms such as abnormal urination and pain and discomfort. For premature ejaculation, the first choice is to apply drugs for control, especially the only FDA-approved drug for premature ejaculation, dapoxetine (Bilevel) is on the market, there is a powerful tool to overcome the problem of premature ejaculation, in the choice of drug treatment program can be individualized according to the patient’s situation on-demand or planned consultation and treatment, in addition to drug treatment to add some behavioral therapy, psychological guidance and so on. Some advocate treating prostatitis first to improve local symptoms and urination-related problems before dealing with premature ejaculation, but since there is a certain connection between them, some scholars advocate treating both at the same time. The first thing you need to do is to get rid of the problem of premature ejaculation, while those with symptoms of prostatitis or LUTS should consider treating prostatitis first, and then see if the problem of premature ejaculation improves when the symptoms improve, or consider further targeted treatment of premature ejaculation if it still doesn’t work. In short, prostatitis and premature ejaculation are two completely different nature of the disease, but the two in a way there is a certain relationship, the treatment of common features also have their own characteristics, the correct understanding of the characteristics of the two and their interrelationship is conducive to the correct diagnosis and treatment of patients to better solve the patient’s problems.