Breast cancer is a relatively common malignant tumor in women, and in very few men it also occurs. Breast cancer is more prone to bone metastasis. Generally, bone metastasis in breast cancer is definitely more serious, indicating that the disease has progressed and belongs to stage 4 breast cancer. In case of severe pain, strong opioid analgesics, such as oxycodone or morphine, can be applied after the development of bone metastasis. Bone metastases can be treated with drugs such as zoledronic acid to inhibit the destruction of bone cells. Local radiotherapy can also be done to relieve pain. For breast cancer primary lesions, palliative surgery can be done and combined with postoperative adjuvant radiotherapy, chemotherapy, endocrine therapy or targeted drug therapy can also prolong survival. Patients with bone metastases can also survive for more than 3 years or 5 years or even longer.