The key to the treatment of chronic obstructive pulmonary disease is the use of bronchodilator drugs, including inhaled long-acting anticholinergic drugs and beta2 agonists, theophylline and glucocorticoids can also be added as appropriate. Short-acting inhalers can be used for temporary relief of symptoms during wheezing. Patients with severe emphysema may be considered for bronchoscopic or surgical lung decompression or even lung transplantation. Patients with significant hypoxemia should be treated with long-term oxygenation, and patients with respiratory failure can be treated with a non-invasive ventilator for home use. In addition, under the condition of oxygenation, strengthening exercise as much as possible, especially exercising the strength of upper and lower limb muscles, can help improve immune function, improve exercise endurance and improve quality of life. In case of acute exacerbation, patients should be seen in hospital.