Impotence and premature ejaculation are different diseases, and the treatment drugs for these two are different. In general, the treatment drugs for impotence include type 5 phosphodiesterase inhibitors such as sildenafil and tadalafil; the oral treatment drugs for premature ejaculation include dapoxetine and paroxetine. 1. Impotence: impotence patients need to take sildenafil, tadalafil and other selective type 5 phosphodiesterase inhibitors, which can improve the patient’s inability to get an erection, poor erection hardness and so on. But need to pay attention to can not be combined with nitrate drugs and so on. 2. Premature ejaculation: patients with premature ejaculation can usually take 5-hydroxytryptamine reuptake inhibitors such as dapoxetine and paroxetine, which can prolong the concentration of serotonin in the central system and thus prolong the ejaculation time. Contraindications include recent strokes and heart attacks, low blood pressure or certain rare hereditary ophthalmopathies and retinitis pigmentosa patients are prohibited, people with severe cardiovascular and cerebrovascular diseases are prohibited. Specific medication also need to go to consult a regular hospital, under the guidance of a doctor.