Acute fatty liver in pregnancy

  While fatty liver is a familiar medical condition, acute fatty liver disease of pregnancy (AFLP) is a rare and clinically dangerous obstetric condition. Although acute fatty liver of pregnancy is called fatty liver in its name, it is very different from what we usually mean by fatty liver. While ordinary fatty liver is a gradually progressive and slowly developing process, AFLP is characterized by its rapid onset and dangerous condition, which can lead to liver failure, progressive jaundice, coagulation dysfunction, acute renal failure and even death within a short period of time, and can directly endanger the fetus, leading to preterm delivery, stillbirth and stillbirth, seriously endangering the life of mother and child.  The pathogenesis of AFLP is not clear, and it usually occurs at any time in late pregnancy, especially in primiparous women around 35 weeks of gestation, especially in cases of hypertensive disorders of pregnancy, multiple births and male fetuses. early diagnosis of AFLP is difficult and there is no specific treatment, once diagnosed, pregnancy should be terminated as soon as possible.  Therefore, pregnant women should consult a doctor promptly if they develop the following symptoms in late pregnancy.  1, obvious gastrointestinal symptoms (nausea, vomiting, anorexia, general weakness, epigastric discomfort or epigastric pain, etc.), of which vomiting and abdominal pain are common; 2, yellow staining of skin and mucous membranes, liver and kidney function damage; 3, persistent hypoglycemia; 4, bruises and bruises on the skin in the case of systemic bleeding tendency; 5, ultrasound suggests: diffuse dense photoelectricity in the liver area, showing “bright liver “-like performance; Understanding these general knowledge of acute pregnancy fatty liver, it is not difficult to conclude: regular maternity checkups, early detection and termination of pregnancy if necessary, is the key to the rescue and treatment of acute fatty liver in pregnancy.