Frequent urination and painful urination with hematuria may be caused by urinary tract infection diseases, urinary tract stones, renal tuberculosis, urinary system tumors and other factors. 1. Urinary tract infection disease: related to the lack of attention to physical hygiene or unclean sex, may induce cystitis or urethritis, due to inflammatory substances stimulation, resulting in local damage, it will cause frequent urination, urinary urgency, urinary pain, hematuria and other symptoms. 2. Urinary stones: In the process of position change or urination, the stones move and cause damage and irritation to the surrounding urinary tract tissues, which can cause frequent urination, urinary urgency, painful urination, hematuria, and may be accompanied by difficulty in urination. 3. Kidney tuberculosis: usually caused by tuberculosis infection, due to the damage to the kidney tissue, it will cause frequent urination, urinary urgency, painful urination, blood in urine and other symptoms, which may be accompanied by fatigue, night sweating, low-grade fever, emaciation and other systemic symptoms. 4. Urological system tumor: For example, bladder tumor usually causes painless hematuria in the early stage, with the aggravation of lesions, it may be combined with infection, and the symptoms of frequent urination, urgency and pain in urination with hematuria will appear. Frequent urination and painful urination accompanied by hematuria indicates the existence of abnormalities, and patients should seek medical examination and treatment as soon as possible to avoid continued aggravation of the lesion.