Ten Questions on Tumor Chemotherapy

First, the role of chemotherapy? 1, 60% of middle and advanced malignant tumors need chemotherapy; 2, it is often used as an important supplement to surgical treatment; 3, it is the only or the main means of treatment for some malignant tumors; 4, the biggest benefit is to realize systemic treatment. What tumors may be cured by chemotherapy? 1. Chorionic epithelial carcinoma; 2. Malignant hyperemesis gravidarum; 3. Acute lymphoblastic/granulocytic leukemia in children/adults; 4. Spermatogranuloma of testis; 5. Nephroblastoma; 6. Skin cancer and so on. C. Chemotherapy that can relieve symptoms? Multiple myeloma; 2. Chronic lymphocytic/granulocytic leukemia; 3. Neuroblastoma; 4. Lung cancer; 5. Gastric cancer, colon cancer; 6. Liver cancer; 7. Breast cancer, ovarian cancer, endometrial cancer and so on. IV. Chemotherapy with certain efficacy? 1. Thyroid cancer; 2. Head and neck tumor; 3. Melanoma; 4. Bladder cancer, etc. V. Neoadjuvant chemotherapy? 1, chemotherapy before surgery; 2, preoperative with 2-3 courses; 3, make the tumor downstage and increase the resection rate; 4, reduce the chance of recurrence and metastasis of the tumor. VI. Adjuvant chemotherapy? 1, postoperative chemotherapy; 2, most malignant tumors have microscopic metastasis before surgery; 3, treating malignant tumors as systemic diseases; 4, single surgical method may have leakage; 5, postoperative chemotherapy time should be early, and the amount should be sufficient. VII. Limitations of chemotherapy? 1, not strong selectivity; 2, indiscriminate, regardless of affinity; 3, toxic side effects. VIII. Dose intensity of chemotherapy? 1.Tumor treatment dose within a certain time range; 2.Calculate the dose per square meter of body surface area; 3.Any decrease in the dose intensity may result in a corresponding decrease in the effective rate of treatment, complete remission rate, and survival rate; 4.Any increase in the dose intensity may result in a corresponding increase in the side effects; 5.It is still controversial as to whether or not the dosage intensity of the foreign standards can be tolerated by the Chinese people. Nine, what situations need to suspend chemotherapy? 1, severe allergic reactions; 2, blood: white blood cells <4 × 109 / L; platelets <50 × 109 / L; 3, fever; 4, severe gastrointestinal reactions: severe oral ulcers, severe abdominal pain and diarrhea, bloody stools; 5, important organ damage: myocardial damage, liver and kidney function damage. X. How long does chemotherapy need to be done? 1.Implemented according to the chemotherapy program and clinical guidelines; 2.Generally advocate 4~8 courses of chemotherapy, about half a year.